Hispidulin Attenuates Cardiac Hypertrophy by Improving Mitochondrial Dysfunction
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چکیده
منابع مشابه
Sirt3 attenuates doxorubicin-induced cardiac hypertrophy and mitochondrial dysfunction via suppression of Bnip3.
Doxorubicin (Dox) is an anthracycline antibiotic widely used in cancer treatment. Although its antitumor efficacy appears to be dose dependent, its clinical use is greatly restricted by development of cardiotoxicity. Sirtuin-3 (Sirt3) is the major deacetylase within the mitochondrial matrix that plays an important role in regulation of cardiac function. This study was performed to identify the ...
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ژورنال
عنوان ژورنال: Frontiers in Cardiovascular Medicine
سال: 2020
ISSN: 2297-055X
DOI: 10.3389/fcvm.2020.582890